Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 2nd World Congress on Nutrition and Obesity Prevention Dubai, UAE.

Day 1 :

Keynote Forum

Mahabaleshwar Hegde

Bharati Vidyapeeth University, India

Keynote: Distorted fatty acid metabolism and metabolic syndrome

Time : 08:30-09:30

Conference Series Nutrition Meet 2019 International Conference Keynote Speaker Mahabaleshwar Hegde photo
Biography:

Mahableshwar Hegde, PhD in biochemistry, has over 30 years post garduate teaching experience, guiding M.Sc, M.Phil, PhD students at Pune University and for the last 20 years has passionately working for omega-3 nutritional security, by establishing a “Center for Innovation in Nutrition Health and Disease (CINHD)” and “Real World Nutrition Laboratory Foundation (RWNLF)” in Bharati Vidyapeeth (deemed to be)University Pune, to validate the innovative omega-3 enriched products throgh FLAX BIOVILLAGE” concept devloped by him. He has published extensively and edited a book “OMEGA 3 FATTY ACID” keys to nutritional health, published by Springer International.

Abstract:

Metabolic syndrome, is a collection of risk factors that increases the chances of developing excessive body fat, heart disease, stroke and diabetes and it is primarily the result of recent abrupt dietary life style changes, more particularly distorted fatty acid intake. Our prehistoric food consisted of 1:1 ratio of omega-6 to omega-3 fatty acid. But today our diet has skewed ratio of 20-40:1. Both linoleic acid omega-6 and alphalinolenic acid omega-3 fatty acids are essential fatty acids. Excessive omega-6 and paucity of omega-3 fatty acid is almost a global phenomenon. Th is has led to the dominance of infl ammatory pathway in modern man and is primarily responsible in phenomenal increase in incidences and severity of chronic degenerative diseases. Omega-3 nutritional security and lowering of intake omega-6 fatty acid, correcting the imbalance is urgent need of the day. Th erefore, our goal has been to bring back primary essential omega-3 fatty acid, alphalinolenic acid, into the food chain. Flax seed is the richest source of vegetarian, omega-3 fatty acid. We have developed technogies, to increase production and productivity of fl axseed; to extract omega-3 oil and soft gel capsules from fl axseed devoid of antinutrients; to stabilize omega-3 fatty acid in emulsion to fortify milk and milk products; omega-3 enriched poultry feed mix for the production omega-3 enriched egg and chicken meat; omega-3 fl our mix for bakery products etc. Our pioneering eff orts, through well researched and validated “FLAX BIO_VILLAGE” concept, aims at attaining omega-3 nutritional security and correct the omega-6: omega-3 imbalance, to eff ectively tackle metabolic syndrome.

Conference Series Nutrition Meet 2019 International Conference Keynote Speaker Bandar Manawer Al Harbi photo
Biography:

Bandar Manawer Al Harbi is working as Assistant Director of Pharmacy for Material Management at Prince Sultan Military Medical City. His current research is in diabetes at DMU University, UK. He is an Adjunct Clinical Assistant Professor at King Saud University, College of Pharmacy and Director of Pharmacy and Director of Central Sterile Supplies Department, PSMMC, Director of Medical Supplies and Purchasing, PSMMC. He is the Chairman of the fi rst International Sterilization Symposium, Instructor of Purchasing Material Management/CSSD course. He is the active Member of American Society of Health System Pharmacist (ASHP) and Saudi Commission for Health Care Specialties. He has participated in many conferences globally

Abstract:

Introduction & Aim: Pre-diabetes describes a condition whereby an individual’s level of blood glucose is above normal level, though not high enough to warrant them a T2D diagnosis. Th e condition is classifi ed into two categories, Impaired Glucose Tolerance (IGT) where blood glucose levels are above the normal 2 hours aft er glucose loading in the oral glucose tolerance test but not so high to warrant the classifi cation as diabetes. Th e other is Impaired Fasting Glucose (IFG) where blood glucose have risen to a fasting state but yet again, not so high to warrant the classifi cation as diabetes. Physical exercise improves BG homeostasis but the extent to which exercise is eff ective strategy as primary prevention mechanism for people whom at risk to develop diabetes is not fully understood. Th e study aims to examine the eff ects of 6-weekes moderate-intensity combined aerobic and resistance exercise program in preventing or delaying the onset of diabetes for subjects at risk compared to sedentary non-diabetic individuals. Method: 20 subjects of a sedentary lifestyle, diagnosed with either pre-diabetes or at risk to developed T2D (PRE-D) and 5 subjects were sedentary healthy individuals (ND) met the inclusion criteria. Both PRE-D and ND have been asked to complete 6-weeks of moderate-intensity combined aerobic and resistance exercise for 60 minutes on two days/week. Each exercise session consists of a combined exercise protocol of 30 minutes of resistance exercise (3 sets of 10 repetitions) followed by 20 minutes cycling. Th e primary outcome is to concentrate on metabolic results, such as improved HbA1c, blood pressure, heart rate, 1-repition max, lipid profi le (reduction in total cholesterol, low density lipoproteins, triglycerides or increase high density lipoproteins) and improvements in insulin sensitivity determined by responses to oral glucose tolerance tests on independent days. Result: Th ere were signifi cant reduction (p=0.00) on the HbA1c aft er applying of 6 weeks’ combination exercise intervention in both groups comparing to baseline. OGTT indicated signifi cant diff erences between pre-exercise and post 12th exercise session in both groups with p=0.01. BG concentrations.

Keynote Forum

Najmul Islam

Aligarh Muslim University, India

Keynote: Allicin from garlic having beneficial effects in combating diseases

Time : 10:45-11:15

Conference Series Nutrition Meet 2019 International Conference Keynote Speaker Najmul Islam photo
Biography:

Najmul Islam is currently working as a Professor in Biochemistry, Faculty of Medicine, Aligarh Muslim University, India. He was the Former Head of the Department of Biochemistry. He has worked for four years in the Division of Infectious Diseases and Department of Rheumatology, Case Eastern Reserve University, Cleveland, Ohio, USA. He was Joint Secretary in 2012-13, Vice President, 2014 and President, 2015 of Indian Academy of Biomedical Sciences, Lucknow. He has published more than 70 papers/articles in reputed journals and has been serving as an Editorial Board Member of repute.

Abstract:

Introduction & Aim: Th e relationship between Reactive Oxygen Species (ROS) and various diseases like metabolic cardiac disorders, osteoporosis, tuberculosis and cancer and are well documented. Th e present study involves the employment of a natural compound namely allicin from garlic having anti-oxidant and anti-infl ammatory properties with proven health benefi ts. Our preliminary observations appear to possibly provide some scientifi c input that may be useful in the management of Ischemic Heart Disease (IHD), osteoporosis, tuberculosis and cancer. Method: Peripheral Blood Mononuclear Cells (PBMC’s) were isolated by density gradient method from blood of patients with Ischemic Heart Disease (IHD), osteoporosis, tuberculosis and cancer (n=20 each) and were employed in culture studies with and without of varying does of allicin (0-500 ng/ml). Th e 24 hr cultures were probed for CK, sTNF-alpha, sRANKL levels as well as for Glutathione Peroxidase (GPx) activity. Result: Cells were collected aft er 24 hours with and without allicin (0-500 ng/ml; n=20 each). An appreciably suppressed GPx activity was recorded in cell cultures of patient’s with IHD, osteoporosis, tuberculosis and cancer when compared to samples of healthy controls where the GPx data refl ects upon the compromised defense system in patients with Ischemic Heart Disease (IHD). On the contrary, treatment or co-culturing with varying doses of allicin (0-500 ng/ml) exhibited a remarkable degree of amelioration in GPx activity in cells of all the above four types of diseased patients. Next, the ELISA data showed that the 24 hr culture supernatants of untreated patients cells were having augmented expressions of sTNF-alpha, which upon co-culturing with 500 ng/ml of allicin resulted in an appreciable degree of downregulation/suppression in the expressions of sTNF-alpha in cells of all the above four types of diseased patients. Cultures from all patient types exhibited a dose dependent suppression with allicin. Similarly, in IHD patients, in comparison to untreated controls, a dose dependent decrease in CK levels were observed in cultures receiving allicin (0-500 ng/ml; n=10). Also, in cell cultures from osteoporosis patients, allicin (0-500 ng/ ml), showed an appreciable degree of downregulation in sRANKL. Conclusion: Th e encouraging preliminary data suggested that in-depth studies are required at the molecular level, which in turn, may provide information for possibly employing allicin as potential adjunct in the management of Ischemic Heart Disease (IHD), osteoporosis, tuberculosis and cancer. repute.

Keynote Forum

Nicolas Wiernsperger

Association REMEDES, France

Keynote: Anti-obesity potential of aged garlic extract: Overview

Time : 14:00-15:00

Conference Series Nutrition Meet 2019 International Conference Keynote Speaker Nicolas Wiernsperger photo
Biography:

Nicolas Wiernsperger is a Physiologist and has completed his PhD in Neurophysiology from University Basel, Switzerland. He has worked as the Head of Department of Brain Microcirculation at Novartis and also he was the Head of International Pharmacological Development at Lipha/Merck KgA in Lyon. He was also Head of a Private/ Public Research Unit on Diabetic Micro vascular Complications at Lyon University. He has been an Author/Co-author of about 150 publications and 2 scientifi c books. He has also worked as a Visiting Professor at several universities. He is presently a Private Consultant for Pathophysiological and Pharmacological aspects of cardio metabolic diseases.

Abstract:

Obesity is a hallmark of pre-diabetes with a conversion rate of close to 10%. However, recent large-scale clinical observations tell us that non-diabetic obesity (metabolic syndrome) is as dangerous as established diabetes for macro angiopathy. Obesity is becoming a huge worldwide health problem and actual lifestyle measures are of limited effi cacy, in addition to be diffi cult to sustain. Th erefore, complementary dietary measures are highly suitable. Among these, garlic and more particularly aged (black) garlic, is of particular potential interest based on its pharmacological properties which target most of the individual parameters causally involved in obesity development. Although a lot has still to be learned and precised about ideal composition and dosage for humans, animal research shows promising benefi cial eff ects. A recent trial with concentrated aged garlic extract has demonstrated impressive loss of weight over short treatment duration in high fat/high sucrose chronic fed rats. Several mechanisms, including central eff ects in hypothalamus, have emerged.

  • Diabetes Mellitus | Biochemistry & Metabolism | Diet for Diabetes | Cardio-Metabolic Disorder | Obesity and Weight Management
Location: Carlton Palace Hotel, Dubai
Speaker

Chair

James Joseph

Gods Own Food Solution Pvt Ltd., India

Speaker

Co-Chair

Ajmila Islam

American University in Dubai, UAE

Session Introduction

Samih Abed Odhaib

American Association of Clinical Endocrinologist, Iraq

Title: He lost 18 kilograms and his diabetes
Speaker
Biography:

Samih Abed Odhaib has completed his PhD from Nahrain Medical School. He is a Fellow of Iraqi Board of Medical Specialization (Internal Medicine) FIBMS, Member of American College of Physician (ACP), Member of American Association of Clinical Endocrinologist (AACE).
 

 

Abstract:

The T2DM in adulthood is strongly related to weight gain and excessive accumulation of pancreatic and hepatic fat. It is very uncommon to have remission without bariatric surgery. Acute negative energy balance can reverse the twin defects of beta cell failure and insulin resistance alone with diet restriction to around 700 kcal that results in decreased pancreatic and liver triacylglycerol stores. Weight loss of at least 10-15 kg has been shown to achieve euglycemia in people with shortduration T2DM for at least 12 months. A 48-year old diabetic male presented to Faiha Specialized Diabetes, Endocrine and Metabolism Center two years ago with very poorly controlled T2DM that was diagnosed more than 3 years ago, along with severe hypertension and marked dyslipidemia. He underwent complete remission of his diabetes aft er losing 18 kg of his original weight (58 kg), with a very good euglycemia measures, on no treatment at all for the last two years. Th e eff ect that extends to make him have normal blood pressure and normal lipid profi le, with decreased cardiovascular risk from 26% to be less than 1%.

Speaker
Biography:

Archana Arora is a Registered Dietitian and has been practicing for more than 20 years in the fitness, healthcare, wellness and catering industries. She has completed her Masters in Food and Nutrition in 1995 followed by an internship at the All India Institute of Medical Sciences, New Delhi. Currently, she is working as a Senior Dietitian and Health Coach at NU Foods, Dubai.

Abstract:

Way of life is central to human wellbeing, from what we eat, how much we move, what we think, what chemicals we are exposed to, how we deal with our emotions and the quality of sleep and the list goes on. Epigenetics (a change in our genetic activity without changing our genetic code) shows that genetics is only 30% of the health equation, with lifestyle choices being 70%. But do we realize it is the wrong lifestyle choices we make, that prepare our body for disease and lead to death. Self-analyzation, willingness to change, continuous wellness journey with trustworthy professional, self-effi cacy evolution (people’s belief that they have the ability to perform particular behaviors) and perseverance can be the most obvious drivers of signifi cant health evolution in your life. With practice, we can enhance our wellbeing and achieve a state of balance and contentment. Lifestyle choices that we make are the basis of our well-being and enhanced quality of life.

Speaker
Biography:

Ragdah A Hamid has completed her Bachelor’s degree in Nursing from The University of Jordan and her Post Graduation Diploma in Diabetes Primary Care from St. Geroge University School of Medicine. She is the Diabetes Nurse Educator in King Saud Medical City, Riyadh.

Abstract:

Introduction: The Diabetes Nurse Educator (CDE) role in King Saud Medical City is a new approach to improving the quality of staff competencies in the care of patients with diabetes. The Diabetes Nurse Educator is an advanced nursing clinician with a focused expert practice area who works to improve the care at the bedside by combining roles as clinician, consultant, researcher, educator, and manager. The Diabetes Nurse Educator has specific responsibilities in serving as an expert in the specialty, ensuring the incorporation of evidence-based practices, promoting research, evaluating the staff nurses’ practice, providing continuous learning opportunities, and promoting critical thinking and problem-solving.

Location/Setting: King Saud Medical City-Riyadh, Endocrinology Department – Diabetes Division Outpatient Clinic and In-patient Units- General Hospital Objective: The goal of implementing the Diabetes Nurse Educator role at King Saud Medical City (KSMC) was to improve the quality, safety, effectiveness, and efficiency of staff nurses caring for patients with diabetes.

Activities: The Diabetes Nurse Educator activities include: The Development and Implementation of Educational Programs for Staff Nurses, Participating in Staff General Nursing Orientation Program (GNO),Organizing Hospital Continuous Nurse Education (HCNE) and Unit Continuous Nurse Education (UCNE) activities in clinical areas Developing Multidisciplinary Educational Programs through the year with other Health Care Professionals, Leading Nursing Grand Rounds and In-service Education, Provide Clinical Resource and Consultation to Staff Nurses in Collaboration with the Endocrine Team, Developing and Implementing Written Protocols and Order Sets in Coordination with Endocrine Team, Working within the community to promote health care including education and training for Community to Support Workers

Conclusion: The CDE plays an integral role in the prevention, diagnosis and adequate management of diabetes. This specialist role can increase skills, knowledge, and confidence, as well as support and empower staff nurses who deal with diabetic patients and help to reduce the chances of developing further complications of the disease.

Speaker
Biography:

Maha Mohammed Arnous has completed his MD degree from School of Medicine in King Fahad Medical City in Riyadh, Saudi Arabia. She is the Senior Resident of Community and Family Medicine at Security Forced Hospital. She is very active in clinical research of diabetes care and prevention.

Abstract:

Background: Many studies have provided evidence for an increased risk of atrial fibrillation among diabetic patients as compared to the non-diabetic population. It is also well known that diabetes predisposes a person to an increased risk of diabetic nephropathy. A few reviews and studies have hinted towards an increased risk of atrial fibrillation among diabetic nephropathy patients.

Aim: To conduct a meta-analysis to explore if there is an association between diabetic nephropathy and atrial fibrillation.

Methods: The available literature was searched for relevant studies from the period of January 1995 to October 2018. The following quality assessment criterion were considered for study shortlisting: Clearly defined comparison groups, same outcome measured in both comparison groups, known confounders addressed and a sufficiently long and complete (more than 80%) follow-up of patients. Two independent reviewers searched the databases, formed their search strategies and finalized the studies. Data was analyzed to obtain a summary odds ratio along with a forest plot by Cochrane’s RevMan 5.3.

Results: Only four studies were found to meet the inclusion criterion for this meta-analysis (total number of study participants: 307330, diabetic nephropathy patients: 22855). Of these, two were retrospective cross-sectional studies, one was a prospective cohort study and one was a case-control study. Three studies had provided the odds ratio as the measure of effect (two retrospective cross-sectional studies and one case-control study), with the one cohort study reporting the hazards ratio as the measure of effect. Therefore, the meta-analysis was done excluding the cohort study. The summary odds ratio in the present study was 1.32 (0.80-2.18), which was not statistically significant. Due to large heterogeneity among the included studies and their small sample sizes, it was found that the summary estimate shifted towards the null value.

Conclusion: The present meta-analysis found no significant association between atrial fibrillation and diabetic nephropathy. However more studies with large sample sizes are required to strengthen the evidence for an association.

Speaker
Biography:

Sultan Al Dalbhi has completed his Clinical Fellowship in Nephrology and Clinical Research Associate degree from School of Medicine in McMaster University and University of Toronto. He is currently a Consultant Nephrologist at Prince Sultan Military Medical City, Riyadh, Saudi Arabia. He is very active as Clinical Researcher in diabetic nephropathy care and prevention.
 

Abstract:

Treatment with Renin Angiotensin Aldosterone System (RAAS) blockade including Angiotensin-Converting Enzyme inhibitors (ACEis) and Angiotensin II Receptor Blockers (ARBs) have been shown to improve clinical outcomes. However, recent contrasting evidence regarding the dual RAAS blockade has also been presented. Very few studies have investigated the effectiveness of this dual blockade among Diabetic Nephropathy (DN) patients in association with albuminuria or proteinuria that is why we did this review. A review of Randomized Controlled Trial (RCT) studies (n=45) reporting on the dose-response analysis among DN patients using the RAAS blockade and other monotherapies over a 25-year period was performed. Overall, 45 studies of DN patients (n=18,628) with albuminuria or proteinuria were included. An association between dual RAAS blockade and DN has observed in which 18 of the 45 datasets revealed that combination therapies were effective among DN patients. Although there was a decline in albuminuria (mean difference: -19.93 mcg/L; 95% CI -50.32-10.47; I2=87.8%, p=0.000) and a slight decline in proteinuria (mean difference: -0.19 mg/mmol; 95% CI -2.32-2.70; I2=99.2%, p=0.000) with dual RAAS blockade combination therapy, these results demonstrated high heterogeneity among studies with non-significant effects. Based on this study, it appears that dual RAAS blockade (or a combination of therapies) is a neutral treatment for patients with DN presenting with symptoms of albuminuria and/or proteinuria. Therefore, other factors must be considered when recommending therapies for DN patients.
 

Speaker
Biography:

Bart A Van Wagensveld has completed his MD in 1995 and PhD in 1998  from the University of Amsterdam, the Netherlands. He was a General Surgeon at the Academic Medical Center in Amsterdam, the Netherlands and specialized in Gastro-Intestinal and Laparoscopic surgery. 
 
Karla El Barmaki is a clinical dietitian who holds a Bachelor’s degree in Earth and Life Sciences (2007), a Bachelor’s degree in Nutrition and Dietetics (2009) and a Master’s degree in Sports Nutrition and Physiology (2013) from Saint Joseph University in Beirut, Lebanon. She completed an internship at a reputable hospital in Beirut, where she provided patients with individualized nutritional care tailored to their medical needs.  
 
 

Abstract:

According to WHO, obesity is defined as an abnormal or excessive fat accumulation that presents a risk to health. It is measured based on the BMI (BMI (kg/m2) =Weight (kg) ÷ Height (m2)) Based on the BMI value people are classified as underweight (<18.5), Normal (18.5-24.9), overweight (25-29.9), obesity (30-39.9) and morbid obesity (40+). The study shows that the main causes of obesity were peoples energy intake was high compared to expenditure which leads to increasing obesity levels. Worldwide obesity has more than tripled since 1975. In 2016, more than 1.9 billion (39%) adults (≥ 18 years) were overweight (39% of men and 40% of women). Of these, over 650 million (13%) were obese (11% of men and 15% of women). Most of the world’s population lives in countries where overweight and obesity kills more people than underweight. 41 million children under the age of 5 were overweight or obese in 2016. In order to reduce the rate of morbid obesity, bariatric surgery is the only effective treatment with long-lasting results. Bariatric surgery leads to a reduction in mortality rates after 5Y, which translates to a decrease in the relative risk of death by 89%. It is also known that obesity is a major risk factor for developing T2DM, with 86% of T2DM patients were either overweight or obese in the UK from this study. Thus, significantly higher diabetes remission rates were reported for gastric bypass (p<0.001) and biliopancreatic diversion (p<0.001) compared to medical therapy. 

Speaker
Biography:

Mohsina Hyder K is currently pursuing Doctoral degree at JSS College of Pharmacy, Ooty under JSS Academy of Higher Education and Research, Mysuru. Her project study is on prediabetes.
 

Abstract:

Prevalence of prediabetes has been increasing globally and it is estimated that 470 million people would have prediabetes by 2030. Progression to T2DM happens swiftly attributed to dietary patterns and sedentary lifestyle. T2DM carries high morbidity and has a huge health and financial impact. The lack of knowledge among the prediabetics is the major factor contributing to failure in disease progression prevention. Recent studies highlight the importance of diabetes education programs. We aimed to organize Prediabetes Education Program (PEP) as 90% people with prediabetes are still unaware on it. Prediabetes Education Program is a cost effective strategy among health literacy for prevention and control of diabetes and its complications by preventing the prediabetes progression. This study involves construction and validation of KAP questionnaire for prediabetes. This is a self-administered 30 items questionnaire administered to prediabetes through medical screening camps conducted over selected districts of South India. The questionnaire development involved several steps like conceptualization, questionnaire design, literature review, experts review, pretest, pilot tests and also validation procedures like face validity, factor analysis, and Cronbach’s alpha. The validated questionnaire was administered to 210 prediabetics including males and females under the age group of 25 to 55 years who participated in PEP at baseline and final visit. Questionnaire showed satisfactory validity and reliability and fairly easy to read scores in readability tests. Outcomes were measured by comparing scores obtained before and after providing prediabetes education and counseling. Patient knowledge deficits were identified and proper counseling was provided. Significant improvements were observed with the KAP domains of prediabetes towards disease management.
 

Speaker
Biography:

Lailan Safi na Nasution is currently a Doctoral student in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia. She is also working as a Lecturer in the Department of Nutrition Faculty of Medicine, Universitas Muhammadiyah Jakarta, Indonesia.
 

Abstract:

Studies reported autophagy gene expressions are increased in the visceral fat in obese persons, associated with obesity related cardio-metabolic risk. It wasn’t known whether this up-regulation differs in obese persons who were already fat from childhood compared to people who were undernourished at a young age. MAP1LC3B/LC3B (microtubule-associated protein 1 light chain 3β) is known as an autophagy-regulating gene. We used rats, a common test subject in obesity experimentation. We hypothesize that autophagy gene expression is higher in the visceral adipocytes of obese adult rats which were undernourished at childhood in comparison to obese adult rats which were already obese before-hand. Four-week-old male Sprague-Dawley rats, after acclimatization, were randomly assigned to three treatment groups given a low-caloric diet (n=5), a standard-caloric diet (n=5) and a high-fat diet (n=5) for 8 weeks. Afterwards, all groups were fed a high-fat diet for 20 weeks. There was a group fed with standard chow diet as control. The visceral adipose fat was then collected for PCR examination. After the first standard chow diet as control 8 weeks, the group was given a low-caloric diet which had a significantly lower body weight than other groups. Aft er the following 20 weeks, this group experienced the highest change in body weight. The relative mRNA expression of the MAP1LC3B/LC3B of this group increased significantly compared to control (p=0.047) and the high fat diet group (p0.037). In conclusion we found that obese adult rats that were undernourished at childhood have a higher relative autophagy gene expression compared to those who were previously normal or obese.